Cortical Spreading Depression of Leao
From Mitochondrial Function to Brain Metabolic Score (BMS)
Avraham Mayevsky & Judith Sonn
Cortical Spreading Depression of Leao
From Mitochondrial Function to Brain Metabolic Score (BMS)
Avraham Mayevsky & Judith Sonn
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Description
This book focuses on energy metabolism and brain functions related to Cortical Spreading Depression of Leao (CSD), an important issue in brain pathophysiology.
Dr. Avraham Mayevsky is a Professor Emeritus in The Mina & Everard Goodman Faculty of Life Sciences and the Leslie and Susan Gonda Multidisciplinary Brain Research Center at Bar-Ilan University in Ramat-Gan, Israel.
Dr Avraham Mayevsky's field of research since they started their Post-Doc training with Prof. Britton Chance in 1972, was Energy metabolism, including mitochondrial function in vivo, of the brain mainly and other tissues In Vivo, exposed to various pathophysiological conditions. During the 50 years of activity they were able to accomplish a large number of goals that have a very significant impact on the understanding of pathophysiological processes in the brain and other organs evaluated under In Vivo conditions. His vision was to develop experimental approaches and tools that will enable them to study various physiological processes in experimental animals and at the same time, will be ready for clinical applications. During the years Dr Mayevsky's laboratory published more than 60 papers dealing with the subject of Cortical Spreading Depression of Leao (CSD).
Dr. Judith Sonn was a part of the Mina & Everard Goodman Faculty of Life Sciences and the Leslie and Susan Gonda Multidisciplinary Brain Research Center at Bar-Ilan University in Ramat-Gan, Israel, for 45 years and retired in 2017.
After graduation, Dr Judith Sonn was a laboratory Manager in Prof. Joseph Kedem’s laboratory, which investigated the physiology of the cardiovascular system. She continued to study for the master’s degree under the supervision of Professor Kedem. The M.Sc. thesis (1979, Summa Cum Laude) was "Oxygen Balance in the Myocardium". This research approach helped to evaluate the myocardial oxygen balance In-Vivo which was described in about 15 articles.
In 1991 Dr Judith Sonn joined Professor Avraham Mayevsky’s research team and as a Ph.D. student under his Supervision. The Doctoral dissertation (1996) was “Effect of Spreading Depression on the Interrelation Between Brain Energy Metabolism and Ion Homeostasis In-Vivo”. During that time, they published 28 articles on the CSD subject.