Atomic Force Microscopy in Nanobiology

" An outstanding review of the current AFM technology and a must-read for light microscopists interested in super-resolution approaches ."

Prof. Michael Tamkun, Colorado State University, USA

"In the last decade, atomic force microscope (AFM) has developed as a tool for imaging the surface of biological samples and for measuring forces at the nanoscale level. Edited by Dr. Takeyasu, this book covers many topics from basic AFM protocols to specific ones that are essential to investigate ligand–receptor binding strength, motion, and dissociation dynamics. It also discusses newly developed technologies and provides new approaches to understand the molecular mechanisms in biological sciences."

Prof. Juan C. Alonso, Centro Nacional de Biotecnologia (CSIC), Spain

" An outstanding review of the current AFM technology and a must-read for light microscopists interested in super-resolution approaches ."

Prof. Michael Tamkun, Colorado State University, USA

"In the last decade, atomic force microscope (AFM) has developed as a tool for imaging the surface of biological samples and for measuring forces at the nanoscale level. Edited by Dr. Takeyasu, this book covers many topics from basic AFM protocols to specific ones that are essential to investigate ligand–receptor binding strength, motion, and dissociation dynamics. It also discusses newly developed technologies and provides new approaches to understand the molecular mechanisms in biological sciences."

Prof. Juan C. Alonso, Centro Nacional de Biotecnologia (CSIC), Spain

Kunio Takeyasu was trained as a zoologist and neuro-pharmacologist in his early career when he was a graduate student at Hiroshima University and Osaka University. After his postdoctoral research on the molecular and cell biological aspects of membrane proteins such as acetylcholine receptors and ion-motive ATPases at Cornell University and the Johns Hopkins University, he joined the University of Virginia as an assistant professor in 1988 and started to utilize atomic force microscopy (AFM) in biological studies. After four years of research and teaching at The Ohio State University, he moved to Kyoto University as a full professor in 1995. Since then, he has been developing technologies for biological application of AFM. His most recent research has been focused on single-molecule imaging of membrane proteins and chromatin at sub-second time region with nanometer space resolution. Prof. Takeyasu has been a member of the Biophysical Society and the American Society for Cell Biology.