Spike Directivity

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Spike directivity is a vector that quantifies changes in transient charge density during action potential propagation. The digital-like uniformity of action potentials is contradicted by experimental data. Many electrophysiologists have observed that the shape of recorded action potentials changes in time. Recent experimental evidence has shown that action potentials in neurons are subject to waveform modulation while they travel down axons or dendrites. The action potential waveform can be modulated by neuron geometry, local alterations in the ion conductance and other biophysical properties including the neurotransmitter release